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Glycogen is the body's stored carbohydrate, held in muscle and liver; it powers higher-intensity exercise and its depletion is a major cause of endurance fatigue.
Glycogen is a branched chain of glucose molecules — the body's storage form of carbohydrate. It is held in two pools:
Total stores hold roughly 1,500–2,000 kcal, enough for about 90–120 minutes of sustained moderate-to-high-intensity exercise. Each gram of stored glycogen binds about 3 grams of water, which is why glycogen loading and depletion cause noticeable swings in body weight.
When muscle glycogen runs low during prolonged exercise, intensity must drop — the endurance phenomenon athletes call "bonking" or "hitting the wall." Strategies to manage glycogen include carbohydrate loading before long events (see carb-loading), consuming carbohydrate during exercise lasting over ~60–90 minutes, and post-exercise refueling to restore stores. The ISSN notes aggressive refeeding of roughly 1.2 g/kg/hour of higher-glycemic carbohydrate is warranted when there are fewer than ~4 hours between sessions.
Educational content only — not medical advice. Always consult a qualified professional for individualized guidance, especially around injury, pregnancy, or medical conditions.