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Exercise the larger muscle groups before the smaller ones, because small muscles fatigue first and would otherwise limit the overload on the large ones.
The exercises in a weight-resistance program should be arranged so that the larger muscle groups are exercised before the smaller ones (this is especially relevant to upper-body exercises). The reason for this arrangement is that the smaller muscles tend to fatigue sooner and more easily than larger groups. Therefore, to ensure proper overload of the larger muscles, they should be exercised first, before the smaller ones fatigue. This principle is appropriate for beginners in a resistance-training program.
In program-design practice this corresponds to the order of exercises (see exercise-order): a beginner should progress from upper body to lower body and from large muscle group to small muscle group, with the evaluation of order based on the client's training level. The reverse arrangement — training a small muscle group before a large one — is the basis of the advanced pre-exhaustion technique (e.g., leg extensions before squats).
Educational content only — not medical advice. Always consult a qualified professional for individualized guidance, especially around injury, pregnancy, or medical conditions.